Promotie onderzoek

The aim of this project is to explore the 3D printing of peadiatric medicines. 3D printing technology enables the creation of medications with a wide range of dosages, shapes, flavors, and drug combinations, all customized to meet the unique needs of individual patients and specific disease conditions. Once the optimal formulations have been developed, the 3D printed medicines will undergo clinical trials for testing. 

We will study compounding medication by 3D printing technology. In this way personalized medication will become more accessable. 
First formulation studies will be executed in order to provide a stable production process. After which, the use of 3D printing will be introduced in the clinical setting. Finally, the printed medication will be tested by a clinical trial.
 

We aim to develop models for sepsis detection and therapeutic treatment personalization, using mechanistic modelling and ML/AI approaches.
 

The aim is to improve the therapeutic drug monitoring process using drug dosing software and new laboratory techniques.
 

We aim to develop methods to radiolabel orally inhaled drug products, allowing us to more accurately determine lung deposition through imaging techniques. 
 

My research focuses on therapeutic drug monitoring of antipsychotics in children with an autism spectrum disorder, and adolescents with anorexia nervosa.
 

Fixed dosing strategies are commonly used in radio-ligand therapies. Radiation dosimetry provides a method of determining radiation exposure of various tissues, allowing for dosages to be optimized for individual patients. To this end, this project explores the use of radiation dosimetry in PK/PD modeling of radiopharmaceuticals, and its use in optimizing dosing strategies.