Promotie onderzoek

We aim to develop methods to radiolabel orally inhaled drug products, allowing us to more accurately determine lung deposition through imaging techniques. 
 

1. Formulation development of direct, sustained and delayed release products using FDM, SSE and automated capsule filling systems. 
2. Quality and cost considerations of 3D printing in a hospital pharmacy setting.
3. Clinical implementation and studies of personalized cortisol in patients with adrenal insufficiency.
 

Het doel is het effect van farmacokinetische boosting op de farmacokinetiek, effectiviteit en toxiciteit van behandeling met olaparib te onderzoeken.

1. Stress-relieving: 3D printing personalized cortisol for patients with adrenal insufficiency
2. A novel delayed release hydrocortison formulation for patients with adrenal insufficiency
3. Feasibility study of 10 mg 3D printed systained release hydrocortisone 
4. Feasibility study of 3D printed delayed release hydrocortisone 
5. RCT of novel 3D printed hydrocortisone vs standard of care in adrenal insufficiency