Promotie onderzoek

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Er zijn48resultaten gevonden
Farmacokinetiek en -dynamiek

Pharmacokinetics and pharmacodynamics of extended halflife clotting factor concentrates in hemophilia

  • Universiteit Universiteit van Amsterdam
  • Promovendus Sjoerd Koopman
  • Promoters Ron Mathot, Marjon Cnossen
  • Jaar 2022-2026
Farmacokinetiek en -dynamiek

Clinical Pharmacology of cystic fibrosis transmembrane conductance regulators (CFTRs)

  • Universiteit Universiteit van Amsterdam
  • Promovendus Steffie Vonk
  • Promoters Ron Mathot, Anke-Hilse Maitland-van der Zee
  • Co-Promoters Marleen Kemper
  • Jaar 2020-2025
Farmacokinetiek en -dynamiek

Digital Twin for earlier detection and personalized management of sepsis in the ICU

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Freek Relouw
  • Promoters N.A.W. van Riel Birgit Koch
  • Co-Promoters Matthijs Kox Rob Taal
  • Jaar 2023-2027

We aim to develop models for sepsis detection and therapeutic treatment personalization, using mechanistic modelling and ML/AI approaches.
 

Farmacokinetiek en -dynamiek

Optimizing Tacrolimus Dosing

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Helena Volarević
  • Promoters Birgit Koch Carla Baan
  • Co-Promoters Brenda de Winter Dennis Hesselink
  • Jaar 2024-2028

The aim is to improve the therapeutic drug monitoring process using drug dosing software and new laboratory techniques.
 

Farmaco-epidemiologie

The long-term outcomes of older adults with COVID-19

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Julia Minnema
  • Promoters Hugo van der Kuy Francesco Mattace-Raso
  • Co-Promoters Miriam Faes Harmke Polinder-Bos
  • Jaar 2022-2025

To describe the impact of COVID-19 on the continuity of care in the primary care setting.
To describe the impact of delirium and frailty on clinical outcomes in COVID-19 patients admitted to the hospital.
To describe the impact of delirium on recovery of COVID-19 patients in geriatric rehabilitation.
To describe perceptions, motivations, needs and experiences of geriatricians with scientific research.
 

Farmacokinetiek en -dynamiek

Towards precision dosing in psychiatric patients

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Kajie Liang
  • Promoters Birigit Koch Pilar Garcia-Gomez
  • Co-Promoters Bram Dierckx Tessa Bosch
  • Jaar 2022-2026

My research focuses on therapeutic drug monitoring of antipsychotics in children with an autism spectrum disorder, and adolescents with anorexia nervosa.
 

Farmacokinetiek en -dynamiek

Radiation dosimetry based pharmacokinetics and dynamics for personalized dosing in radioligand therapy

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Kevin Doornhof
  • Promoters F.A. Verburg
  • Co-Promoters S.L.W. Koolen M.W. Konijnenberg N.H. Hendrikse
  • Jaar 2023-2027

Fixed dosing strategies are commonly used in radio-ligand therapies. Radiation dosimetry provides a method of determining radiation exposure of various tissues, allowing for dosages to be optimized for individual patients. To this end, this project explores the use of radiation dosimetry in PK/PD modeling of radiopharmaceuticals, and its use in optimizing dosing strategies.
 

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