Promotie onderzoek

We aim to develop a pharmacometric model based on COVID-19 data able to identify personal characteristics that could predict individual immune response. Moreover, a framework will be established as a tool for pandemic preparedness. 
 

SPACe 2: STAR: An international, multicentre, randomized controlled trial (RCT) to evaluate the effect of therapeutic drug monitoring (TDM) of antipsychotic drugs in children and adolescents.
 

We aim to improve treatment of critically ill sepsis patients by increasing beta-lactam dosages in the initial phase of sepsis. 
 

The aim is to personalize oncological treatments using a pharmacometric approach.
 

My research focuses on the socioeconomic determinants of psychotropic medication use in children and adolescents. Specifically, I aim to identify the complex relationships between socioeconomic factors and psychotropic medication use in young people, and to explore potential avenues for improving health outcomes in this vulnerable population.
 

The aim of this project is to achieve more effective patient treatments with antibiotics by quantifying the concentrations at the site of infection with minimal sample volumes. To enable quantification of antibiotics at the site of infection, multiple assays should be developed and validated in these infected matrices, such as synovial fluid, synovial tissue, bone, and vitreous humor. Furthermore, the focus will be on small-volume samples and more patient friendly, and sustainable sample preparations.