Klinische farmacologie
Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers
- Universiteit Erasmus Medisch Centrum Rotterdam
- Promovendus Wendy Tan
- Promoters Hugo van der Kuy
- Co-Promoters Rory de Vries Corine Geurts van Kessel Luca Zaeck
- Jaar 2022-2025
To determine the need for repeated booster vaccinations in healthy individuals and to aid policymakers in future public health interventions for COVID-19. Gain insight into the immunogenicity of the additional bivalent booster vaccination in a representative sample of the healthy Dutch population. We aim to investigate three main topics:
i) immunogenicity of bivalent vaccines after priming with adenovirus- or mRNA-based vaccines,
ii) immunological recall responses and reactivity with relevant variants after booster vaccination, and
iii) the necessity of booster vaccinations for the healthy population in the future.