Promotie onderzoek

This thesis explores how systemic inflammation and continuous renal replacement therapy (CRRT) influence drug pharmacokinetics in critically ill patients. Key research questions include: How does inflammation alter midazolam metabolism in critically ill COVID-19 patients? What impact does CRRT have on the drug CL and efficacy of commonly administered drugs at the ICU? The findings aim to optimize therapeutic approaches in critically ill patients.
 

Aim is to investigate the occurence and prevention of anti-cancer treatment, particularly immune checkpoint inhibitors. 
 

Het doel van dit onderzoek is het onderzoeken welke immunologische en immunofarmacologische diagnostiek kan worden gebruikt om immunotherapie van longkanker te verbeteren.

Het doel is het effect van farmacokinetische boosting op de farmacokinetiek, effectiviteit en toxiciteit van behandeling met olaparib te onderzoeken.

1. Cost benefit analysis clinical medication reviews
2. Follow up of interventions from clinical pharmacists.
3. Medication information needs of hospitalized patients.